IL-8/CXCL8 Monoclonal Antibody(Detector) (AN002150P)
For research use only.
| Verified Samples | Verified Samples in ELISA: Recombinant Human IL-8/CXCL8 protein, Human serum, Human plasma |
| Dilution | ELISA Detector 0.1-0.4 μg/mL |
| Isotype | Rat IgG1 |
| Host | Rat |
| Reactivity | Human |
| Applications | ELISA Detector |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human IL-8/CXCL8 protein expressed by Mammalian |
| Abbre | IL-8/CXCL8 |
| Synonyms | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, 3-10C, AMCF-I, K60, |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Protein A/G Purification |
| Research Areas | Cancer, Cardiovascular, Immunology |
| Clone No. | 3E8 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | Interleukin 8 (IL-8),also known as CXCL8,which is a member of the CXC chemokine family. This chemokine is secreted by a variety of cell types including monocyte/macrophages,T cells,neutrophils,fibroblasts,endothelial cells,and various tumor cell lines in response to inflammatory stimuli. IL-8 has two primary functions. It induces chemotaxis in target cells,primarily neutrophils but also other granulocytes,causing them to migrate toward the site of infection. IL-8 also induces phagocytosis once they have arrived. This gene is believed to play a role in the pathogenesis of bronchiolitis,a common respiratory tract disease caused by viral infection. IL-8 is also known to be a potent promoter of angiogenesis. IL-8 has been associated with tumor angiogenesis,metastasis,and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression. |
Other Clones
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Other Formats
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Unconjugated
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