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For research use only.

Host Mouse
Reactivity Human
Applications IHC-P
Synonyms INI-1
Cellular Localization nucleus
Tissue Specificity Breast cancer
Storage The RTU should be stored at 2~8°C protecting from light (Do not freeze),Valid for 12 months.
Shipping Ice bag
background INI-1, located on chromosome 22q11.2, is a member of the SWI/SWF chromatin remodeling complex and is expressed in all normal tissues. INI-1 encodes a protein of HSWI/SNF chromatin remodeling complex with unknown function, which is prone to mutation and deletion in malignant rhabdoid tumors (MRT). "In most malignant rhabdoid tumors (including atypical teratoma/rhabdoid tumor of the central nervous system in children) and epithelioid sarcomas, INI-1 is inactivated, and the majority of medulloblastomas and primitive neuroectodermal tumors express INI-1."
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