Toll-free:1-888-852-8623

All categories

  • All categories
  • Flow Cytometry Antibodies
  • ELISA Kits
  • MACS Cell Isolation
  • Antibodies and Reagents
  • Cell Health Detection
  • Metabolism Assays
  • Immunoassays
  • Cell Identification
  • Proteins and Peptides
  • Cell Culture
Please enter the item number/product keyword!
Keyword cannot be empty !
INSERT SYMBOLS:
  • α
  • β
  • γ
  • δ
  • ε
  • ζ
  • η
  • θ
  • κ
  • μ
  • ω
  • σ
  • τ
  • λ
  • ⅩⅢ
  • ⅩⅢ
  • ⅩⅣ
  • ⅩⅤ
  • ⅩⅦ
  • ⅩⅧ
  • UP ↑

L-Selectin/CD62L Polyclonal Antibody(Capture/Detector) (AN004450P)

All Size Price Qty
100μg $ 350.00
25μg $ 130.00
1mg Inquire /
Add to cart

For research use only.

Verified Samples Verified Samples in ELISA: Recombinant Rat L-Selectin/CD62L protein, Rat serum, Rat plasma
Dilution ELISA Capture 2-8 μg/mL,  ELISA Detector 0.1-0.4 μg/mL
Isotype Rabbit IgG
Host Rabbit
Reactivity Rat
Applications ELISA Capture/Detector
Clonality Polyclonal
Immunogen Recombinant Rat L-Selectin/CD62L Protein expressed by Mammalian
Abbre L-Selectin/CD62L
Synonyms Leukocyte-endothelial cell adhesion molecule,  LECAM,  CD62 antigen-like family member L,  CD62L,  LAM1,  LAM-1,  LECAM1,  LEU8,  Leu-8,  Leukocyte adhesion molecule 1 (LAM-1),  Leukocyte-endothelial cell adhesion molecule 1,  LSEL,  L-selectin,  Lyam-1,  Lymph node homing receptor,  Lymphocyte antigen 22 (Ly-22),  Lymphocyte surface MEL-14 antigen,  PLNHR,  TQ1,  Lnhr,  Ly-22,  Sell,  LYAM1,  LECAM1,  Leu-8
Swissprot
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
Purification Method Antigen Affinity Purification
Conjugation Unconjugated
Storage Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
background L-Selectin (also known as Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is a member of the Selectin family of cell surface molecules which include E-Selectin and P-Selectin. All Selectins have an extracellular domain composed of an amino-terminal calcium-dependent lectin domain, an epidermal growth factor (EGF)-like domain, two to nine short consensus repeat (SCR) units, a transmembrane domain, and a cytoplasmic tail. L-Selectin expression is limited to hematopoietic cells, with most leukocytes expressing L-Selectin at some stage of differentiation. The majority of myeloid cells, B cells, and virgin T cells express L-Selectin, while only a sub-population of memory T cells and NK cells express L-Selectin. Lymphocytes and neutrophils exhibit a reversible loss of L-Selectin after cellular activation that results from endoproteolytic release of the extracellular portion of receptor from the cell surface. Cleavage of L-Selectin from the cell surface results in a high circulating level of functionally active soluble L-Selectin. All selectins bind sialytated and fucosylated oligosaccharides that are linked to glycoproteins and glycolipids. L-Selectin specifically binds to at least three different heavily glycosolylated mucin-like proteins: GlyCAM-1, CD34, and MAdCAM-1. Multiple studies indicated that L-Selectin, P-Selectin E-Selectin collaborate to mediate the initial binding of leukocytes to endothelium at sites of tissue injury and inflammation, producing the characteristic “rolling” of leukocytes along the endothelium. L-Selectin knockout mice have a 70% decrease in rolling leukocytes in exposed mesentery and have impaired neutrophil and monocyte migration into areas of inflammation. Additionally, L-Selectin knockout mice have relatively few lymphocytes present in peripheral lymph nodes and Peyer’s patches. Short-term in vivo homing experiments in L-Selectin deficient mice demonstrate that L-Selectin is involved in lymphocyte homing to Peyer’s patches and mesenteric lymph nodes in the gut. Rat and human L-Selectin share 77% amino acid sequence homology. Rat and mouse L-Selection share 83% amino acid sequence homology.
Cat.No. Product Name Sizes
PDMR100048 Recombinant Rat CD62L/L-Selectin Protein(Fc Tag) 500μg , 100μg , 20μg , 1mg
Other Clones

{{antibodyDetailsPage.numTotal}} Results

Other Formats

{{formatDetailsPage.numTotal}} Results

Unconjugated

  • IF:{{item.impact}}

    Journal:{{item.journal}} ({{item.year}})

    DOI:{{item.doi}}

    Reactivity:{{item.species}}

    Sample Type:{{item.organization}}

  • Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}}