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For research use only.

Verified Samples Verified Samples in IHC: Rat kidney, Human kidney, Human liver
Dilution IHC 1:100-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant Rat PCK1 protein expressed by E.coli
Abbre PCK1
Synonyms GTP,  PCK1,  PCKGC,  PEP carboxykinase,  PEPCK-C,  PEPCK1,  PEPCKC,  Phosphoenolpyruvat,  Phosphoenolpyruvate carboxykinase,  Phosphoenolpyruvate carboxykinase 1,  Phosphoenolpyruvate carboxykinase 1 (soluble),  cytosolic [GTP]
Swissprot
Concentration 1 mg/mL
Buffer PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method Antigen Affinity Purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene,along with GTP,catalyzes the formation of phosphoenolpyruvate from oxaloacetate,with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin,glucocorticoids,glucagon,cAMP,and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
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Unconjugated

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