PCK1 Polyclonal Antibody (D-AB-10224L)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Rat kidney, Human kidney, Human liver |
| Dilution | IHC 1:100-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant Rat PCK1 protein expressed by E.coli |
| Abbre | PCK1 |
| Synonyms | GTP, PCK1, PCKGC, PEP carboxykinase, PEPCK-C, PEPCK1, PEPCKC, Phosphoenolpyruvat, Phosphoenolpyruvate carboxykinase, Phosphoenolpyruvate carboxykinase 1, Phosphoenolpyruvate carboxykinase 1 (soluble), cytosolic [GTP] |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene,along with GTP,catalyzes the formation of phosphoenolpyruvate from oxaloacetate,with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin,glucocorticoids,glucagon,cAMP,and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. |
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