Plasminogen Activator/Urokinase Monoclonal Antibody(Detector) (AN002180P)
For research use only.
| Verified Samples | Verified Samples in ELISA: Recombinant Human Plasminogen Activator/Urokinase protein, Human serum, Human plasma, Human urine |
| Dilution | ELISA Detector 0.1-0.4 μg/mL |
| Isotype | Rat IgG1 |
| Host | Rat |
| Reactivity | Human |
| Applications | ELISA Detector |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human Plasminogen Activator/Urokinase protein expressed by Mammalian |
| Abbre | Plasminogen Activator/Urokinase |
| Synonyms | UPA, u-PA, ATF, URK, UP-A, Urokinase, Abbokinase, |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Protein A/G Purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience |
| Clone No. | 9B8 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Unconjugated
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