Purified Anti-Mouse CD20 Antibody[DA015] (AN015450P)
| Alternate Names | CD20, CD20 antigen, CD20 receptor, CVID5, Fc epsilon receptor I beta chain, IGEL, IGER, IGHER, LEU16, leukocyte surface antigen Leu 16, MS4A1, LEU, Lymphocyte antigen, B lymphocyte antigen CD, B-lymphocyte antigen CD, leukocyte surface antigen Leu, B-cell differentiation antigen Ly, B Lymphocyte Cell Surface Antigen B, Membrane-spanning 4-domains subfamily A member, CVID, CVID5, APY, ATOPY, B lymphocyte antigen CD20, B Lymphocyte Cell Surface Antigen B1, B-cell differentiation antigen Ly-44, B-lymphocyte antigen CD20, Bp35, CD20 antigen, CD20 receptor, Fc epsilon receptor I beta chain, IGEL, IGER, IGHER, LEU16, leukocyte surface antigen Leu 16, Lymphocyte antigen 44, Membrane-spanning 4-domains subfamily A member 1, S7, Cd20, Ly-44, Ms4a2, Ms4a1, B1, Bp35, Ly-44, ATOPY, B lymphocyte antigen CD20, B Lymphocyte Cell Surface Antigen B1 |
| Clone | |
| Verified Samples | Verified Samples in FCM: C57/BL6 Mouse splenocytes cell |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume;Block Reported in the literature |
| Background | CD20 is a 33-37 kD protein, a member of the MS4A family, with four transmembrane spanning regions that present as a homo-oligomeric complexes in the cell surface when associating with MHC class I and II, CD53, CD81, and CD82. CD20 is expressed on B cells and a subset of T cells, but not on plasma cells. CD20 regulates B-cell activation and proliferation. Its ligation promotes transmembrane Ca2+ trafficking. CD20 is an important therapeutic target in the treatment of B cell lymphomas and leukemias. |
| Immunogen | Recombinant Mouse CD20 protein |
| Abbre | CD20 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rat IgG2b, κ |
| Isotype Control | Purified Rat IgG2b, κ Isotype Control[LTF-2], Functional Grade |
| Applications |
FCM
|
| Cellular Localization |
Cell membrane
|
| Tissue Specificity |
Expressed in peripheral lymph node and 101 other cell types or tissues.
|
| Concentration |
≥1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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