Recombinant 2B4/CD244 Monoclonal Antibody (AN300092P)

Name: Recombinant 2B4/CD244 Monoclonal Antibody
Brand: Elabscience
SKU: AN300092P
Price: 150.0 USD
Availability: InStock

Copy the product info.

Citations ({{ citationsPage.numTotal }}) Manual MSDS

Resources

Recombinant 2B4/CD244 Monoclonal Antibody - 1

All	Size	Price	Qty
	100μL	$ 380.00	- +
	20μL	$ 150.00	- +

Bulk request

Add to cart

For research use only. Order now, ship in 3 days

Dilution	WB: 1:1000；IHC-P: 1:50
Isotype	IgG
Host	Rabbit
Reactivity	Human
Applications	WB, IHC-P
Clonality	Recombinant;Monoclonal
Immunogen	Recombinant Human 2B4 / CD244 protein
Abbre	CD244
Synonyms	h2B, SLAM family member, Natural killer cell receptor 2B, NKR2B, SLAMF, CD244, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4, h2B4, Natural killer cell receptor 2B4, NK cell activation-inducing ligand, SLAM family member 4, 2B4, C9.1, CD244 antigen, CD244 molecule, CD244 molecule natural killer cell receptor 2B4, CD244 natural killer cell receptor 2B4, F730046O15Rik, Ly90, member 4, Natural killer cell activation-inducing ligand, NK cell activation inducing ligand, NK cell activation inducing ligand NAIL, NK cell type I receptor protein 2B4, Non-MHC restricted killing associated, OTTHUMP00000027884, p38, signaling lymphocytic activation molecule 4, SLAM family
Swissprot	Q9BZW8
Calculated MW	42 kDa
Observed MW	70-120 kDa The actual band is not consistent with the expectation. Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane.
Cellular Localization	Cell membrane
Tissue Specificity	Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed in all natural killer (NK) cells, monocytes and basophils, TCR-gamma/delta+ T-cells, monocytes, basophils, and on a subset of CD8+ T-cells.
Concentration	1 mg/mL
Buffer	0.2 μm filtered solution in PBS
Purification Method	Protein A
Research Areas	Immunology, Stem Cells
Clone	A1206
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	Ice bag
background	This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq, Jul 2008]