Recombinant bFGF/FGF2 Monoclonal Antibody (AN300097P)
For research use only.
| Verified Samples | Verified Samples in IHC: Human malignant melanoma, Human hepatoma, Human glioma |
| Dilution | IHC-P 1:250-1:1000, |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P |
| Clonality | Rabbit Monoclonal |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Human bFGF. |
| Abbre | FGF2 |
| Synonyms | HBGF, FGF, BFGF, FGF-2, FGFB, HBGF-2, Basic FGF, FGF2, Basic Fibroblast Growth Factor, B-FGF, FGF-β, Fibroblast Growth Factor 2, heparin-binding growth factor 2, prostatropin, BFGF, B-FGF, FGF-2, FGFB, fibroblast growth factor 2, HBGF-2, heparin-binding growth factor 2, prostatropin, basic, Basic fibroblast growth factor bFGF, FGF 2, FGF B, FGF2 basic, Fibroblast growth factor, Fibroblast growth factor 2 (basic), HBGF 2, HBGF2, HBGH 2, HBGH2, Heparin binding growth factor 2 precursor, heparin-binding growth factor 2, FGF-β |
| Swissprot | |
| Cellular Localization | Secreted, Nucleus. |
| Tissue Specificity | Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue. |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Protein A |
| Research Areas | Cardiovascular, Signal Transduction, Neuroscience, Stem Cells, Cancer, Developmental Biology |
| Clone No. | 6H9 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | FGF basic, also known as FGF-2 and HBGF-2, is a member of the FGF family of mitogenic proteins. FGF basic is widely expressed and affects diverse aspects of embryonic development by regulating cell proliferation, differentiation, and survival. Various N-terminal extensions affect localization of FGF basic in cellular compartments but do not affect biological activity. Binding of FGF to heparin or cell surface heparan sulfate proteoglycans is necessary for binding of FGF to high affinity FGF receptors. Mature human FGF basic shares greater than 96% aa sequence identity with bovine, mouse, and rat FGF basic. |
Other Clones
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Unconjugated
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