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Recombinant Carbonic Anhydrase XIV/CA14 Monoclonal Antibody (AN300091P)

All Size Price Qty
100μL $ 380.00
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For research use only.

Verified Samples Verified Samples in IHC: Human liver
Verified Samples in IF: MCF7
Dilution IHC-P 1:100-1:500,  ICC/IF 1:20-1:100,  
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC-P,  ICC/IF
Clonality Rabbit Monoclonal
Immunogen Recombinant Human Carbonic Anhydrase XIV / CA14 Protein
Abbre CA14
Synonyms UNQ,  PRO,  CAH,  UNQ690/PRO,  CA 14,  CA XIV,  CAH14,  Carbonate dehydratase XIV,  Carbonic anhydrase 14,  Carbonic anhydrase XIV,  Carbonic dehydratase,  CAXIV,  CA-XIV,  UNQ690/PRO1335,  CA14,  UNQ690,  PRO1335
Swissprot
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Neuroscience
Clone No. 6H2
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. CAXIV is a member of CA family that showed an overall similarity of 29–46% to other active CA isozymes. The highest percentage similarity was with a transmembrane CA isoform, CAXII. The CAXIV was found high concentrations in human heart, brain, liver, and skeletal muscle but lower in the colon, small intestine, urinary bladder, and kidney. No CAXIV mRNA was seen in the salivary gland and pancreas. CAXIV is a likely candidate for the extracellular CA postulated to have an important role in modulating excitatory synaptic transmission in brain.
Other Clones

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Unconjugated

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