Recombinant CXCL7/PBP Monoclonal Antibody (AN301992L)
For research use only.
| Verified Samples | Verified Samples in WB: Human placenta, Human platelet |
| Dilution | WB 1:1000-1:200000 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, |
| Applications | WB |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Peptide. This information is proprietary to PTMab. |
| Abbre | CXCL7/PBP |
| Synonyms | B-TG, CTAP, CXCL, SCYB, C-X-C Motif Chemokine, MDGFSmall-Inducible Cytokine B, LA-PF, NAP, PPBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, C-X-C Motif Chemokine 7, Leukocyte-Derived Growth Factor, Macrophage-Derived Growth Factor, MDGFSmall-Inducible Cytokine B7, NAP2, Platelet Basic Protein, βTG, B TG1, Beta TG, Beta thromboglobulin, beta-1, Chemokine (C X C motif) ligand 7, Connective tissue activating peptide III, CTAP 3, CTAP III, CTAP-III(1-81), CXC chemokine ligand 7, CXCL 7, LA PF 4, Leukocyte derived growth factor, Low-affinity platelet factor IV, NAP 2, NAP-2(1-63), NAP-2(1-66), NAP-2(73), NAP-2(74), Neutrophil activating peptide 2, Neutrophil-activating peptide 2(1-63), Pro platelet basic protein, Pro platelet basic protein (chemokine (C-X-C motif) ligand 7), Pro-Platelet basic protein, Small inducible cytokine subfamily B member 7, Small-inducible cytokine B7, Thrombocidin 1, Thrombocidin 2, Thromboglobulin, βTG, PBP, CXCL7, NAP2, β-thromboglobulin |
| Swissprot | |
| Calculated MW | 14 kDa |
| Observed MW |
11 kDa
The actual band is not consistent with the expectation.
Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane. |
| Cellular Localization | Secreted |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Immunology, Cardiovascular, Signal Transduction |
| Clone No. | A712 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | CXCL7, also named as PPBP or NAP2, is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. |
Other Clones
{{antibodyDetailsPage.numTotal}} Results
-
{{item.title}}
Citations ({{item.publications_count}}) Manual MSDS
Cat.No.：{{item.cat}}
{{index}} {{goods_show_value}}
Other Formats
{{formatDetailsPage.numTotal}} Results
Unconjugated
-
{{item.title}}
Citations ({{item.publications_count}}) Manual MSDS
Cat.No.：{{item.cat}}
{{index}} {{goods_show_value}}
-
IF：{{item.impact}}
Journal：{{item.journal}} ({{item.year}})
DOI：{{item.doi}}Reactivity：{{item.species}}
Sample Type：{{item.organization}}
-
Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}}
