Recombinant Fas/TNFRSF6/CD95 Monoclonal Antibody(Capture) (AN002600P)
For research use only.
| Verified Samples | Verified Samples in ELISA: Recombinant Human Fas/TNFRSF6/CD95 protein, Human serum, Human plasma |
| Dilution | ELISA Capture 2-8 μg/mL |
| Isotype | Mouse IgG2a |
| Host | Mouse |
| Reactivity | Human |
| Applications | ELISA Capture |
| Clonality | Recombinant |
| Immunogen | Recombinant Human Fas/TNFRSF6/CD95 protein expressed by E.coli |
| Abbre | Fas/TNFRSF6/CD95 |
| Synonyms | FASR, TNFRSF6, APO1, APT1, FAS1, FASTM, ALPS1A |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
| Purification Method | Protein A/G Purification |
| Research Areas | Cancer, Cell Biology, Immunology |
| Clone No. | 6C2 |
| Conjugation | Unconjugated |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
| background | FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand. |
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Unconjugated
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