Recombinant Phospho-IκB-α (Ser36) Monoclonal Antibody (AN301280L)
For research use only.
| Verified Samples | Verified Samples in IHC: Human colon |
| Dilution | IHC 1:500-1:1000 |
| Isotype | IgG,κ |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | A synthetic peptide corresponding to residues around (Ser36) of Human Phospho-IκB-α |
| Abbre | IκB-α |
| Synonyms | EDAID, MAD, IKBA, MAD-3, NFKBI, IKB alpha, NFKBIA, EDAID2, I kappa B alpha, IkappaBalpha, I-kappa-B-alpha, IKBalpha, IkB-alpha, MAD 3, NF kappa B inhibitor alpha, MAD3, alpha, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappa-B inhibitor alpha, Nuclear factor of kappa light chain gene enhancer in B cells, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, pIκBα |
| Swissprot | |
| Cellular Localization | Cytoplasm, Nucleus, Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. |
| Concentration | 0.2 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A |
| Research Areas | Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Immunology |
| Clone No. | B1043 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |
Other Clones
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Unconjugated
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