TROP2/TACSTD2 Monoclonal Antibody (AN200176P)

Name: TROP2/TACSTD2 Monoclonal Antibody
Brand: Elabscience
SKU: AN200176P
Price: 150.0 USD
Availability: InStock

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	100μL	$ 380.00	- +
	20μL	$ 150.00	- +

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Verified Samples	Verified Samples in WB:?MCF7, NCI-N87 Verified Samples in IHC: Human rectal cancer, Human placenta, Human mammary gland, monkey Palm skin, Human skin, Human hysterocarcinoma, Human skin cancer, Human thyroid cancer Verified Samples in IF: NCI-N87 Verified Samples in FCM: MCF-7, NCI-N87
Dilution	WB 1:500-1:2000, IHC-P 1:100-1:500, ICC/IF 1:20-1:100, FCM 1:25-1:100
Isotype	IgG1
Host	Mouse
Reactivity	Human
Applications	WB, IHC-P, FCM, ICC/IF
Clonality	Monoclonal
Immunogen	Recombinant Human TROP2 protein
Abbre	TACSTD2
Synonyms	M1S, TROP, Cell surface glycoprotein Trop, Tumor-associated calcium signal transducer, Membrane component chromosome 1 surface marker, GA733, TACSTD, EGP, TACSTD2, EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2, Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, Tumor-associated calcium signal transducer 2, TACD2, TROP-2
Swissprot	P09758
Calculated MW	36 kDa
Observed MW	36-40 kDa The actual band is not consistent with the expectation. Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane.
Tissue Specificity	Placenta, pancreatic carcinoma cell lines.
Concentration	1 mg/mL
Buffer	0.2 μm filtered solution in PBS
Purification Method	Protein A
Research Areas	Cancer
Clone No.	2C4
Conjugation	Unconjugated
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping	Ice bag
background	This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.