VPS33B Polyclonal Antibody (E-AB-17278)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human prostate cancer |
| Dilution | IHC 1:30-150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human VPS33B |
| Abbre | VPS33B |
| Synonyms | FLJ14848, VPS 33B, Vacuolar protein sorting 33 homolog B, Vacuolar protein sorting 33 homolog B (yeast), Vacuolar protein sorting 33B, Vacuolar protein sorting 33B (yeast), Vacuolar protein sorting associated protein 33B, hVPS 33B, hVPS33B |
| Swissprot | |
| Cellular Localization | Endosome, early endosome membrane, late endosome, late endosome membrane, recycling endosome, Golgi apparatus, Golgi apparatus, Lysosome, lysosomal membrane, lysosome, Other locations: clathrin-coated vesicle, cytoplasm, perinuclear region of cytoplasm, platelet alpha granule. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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