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TGM2-P2RX7 loop promotes gemcitabine resistance in pancreatic cancer by modulating glutamine metabolism and mitophagy

IF: 7.000

Journal: Cell Death Discovery(2025)
DOI: 10.1038/s41420-025-02922-x
Products: PANC-1 Cells Line, MIA PaCa-2 Cells Line
Product Category: Cell Line

Hypoxia-induced USP13 expression drives ferroptosis resistance and tumor immune evasion in hepatocellular carcinoma through the stabilization of ACLY

IF: 7.000

Journal: Cell Death Discovery(2025)
DOI: 10.1038/s41420-025-02869-z
Products: HCCLM3 Cells Line, Hep 3B2.1-7 Cells Line, 293T Cells Line
Product Category: Cell Line

Endothelial mechanosensitive transcription factor BHLHE40 induced by Piezo1 suppresses endothelial ferroptosis and inflammation via SLC7A11

IF: 7.000

Journal: Cell Death Discovery(2025)
DOI: 10.1038/s41420-025-02909-8
Products: Human Umbilical Vein Endothelial Cells (Primary cell immortalization)
Product Category: Primary Cell

Discovery of novel dual-target inhibitors of LSD1/EGFR for non-small cell lung cancer therapy

IF: 6.900

Journal: ACTA PHARMACOLOGICA SINICA(2025)
DOI: 10.1038/s41401-024-01439-w
Products: NCI-H1299 Cells Line, NCI-H1975 Cells Line, NCI-H460 [H460] Cells Line, PC-9 Cells Line
Product Category: Cell Line

Integrated multi-omics characterization of neuroblastoma with bone or bone marrow metastasis

IF: 6.900

Journal: Genes & Diseases(2025)
DOI: 10.1016/j.gendis.2024.101511
Products: SH-SY5Y [SHSY-5Y] Cells Line, SK-N-SH Cells Line
Product Category: Cell Line

A novel supramolecular nanodrugs for improving the cognitive function of schizophrenia by protecting active lactone of arecoline

IF: 6.900

Journal: BIOMEDICINE & PHARMACOTHERAPY(2025)
DOI: 10.1016/j.biopha.2025.117845
Products: PC-12 (Low differentiation) Cells Line, Neuro-2a [N2a; Neuro-2a] Cells Line, bEnd.3 [BEND3] Cells Line
Product Category: Cell Line

Autophagy-induced NR2F1 activation promotes the apoptosis of lens epithelial cells and facilitates cataract-associated fibrosis through targeting STAT3

IF: 6.900