The difference between CD62L and CD62?

CD62L, CD62E, and CD62P are two immune cell surface molecules that belong to the selectin family. CD62L, also known as L-selectin, is a protein in the integrin family that is expressed primarily on the surface of white blood cells. It is involved in regulating the adhesion and migration of white blood cells, especially in inflammation and immune responses. By binding to its ligand, such as PECAM-1 on vascular endothelial cells, CD62L helps leukocyte to roll out of the circulation and migrate specifically to areas such as inflammation sites or lymph nodes. CD62P, also known as P-selectin, is a adhesion molecule that is expressed primarily on endothelial cells and platelets. In the process of inflammation and thrombosis, CD62P on endothelial cells can be expressed rapidly and bind to ligands (such as PSGL-1) on white blood cells to promote mutual adhesion and activation of white blood cells and platelets. CD62E, also known as E-selectin, is an adhesion molecule that is expressed primarily on endothelial cells.