Recombinant Proteins
Recombinant protein is a modified form of protein produced through recombinant DNA technology. By inserting the DNA encoding the protein into bacterial or mammalian cells, we can obtain quantities of the target proteins after amplification, expression, and purification. Elabscience® offers a diverse selection of more than 4,000 proteins for your research, including cytokines, growth factors, immune checkpoint proteins, CD antigens, Fc receptors, enzymes, hormones, and more.
Product Categories
Cytokines
Elabscience® cytokines are small secreted proteins released by immune cells that regulate the immune system through autocrine, paracrine, and endocrine signaling. They also regulate the maturation, growth, and responsiveness of various cell types. Elabscience® provides a comprehensive catalog of recombinant cytokines with excellent lot-to-lot consistency, superior activity, and very low endotoxin levels. This catalog includes chemokines, interferons (IFNs), interleukins, and tumor necrosis factors (TNFs), colony-stimulating factors (CSFs), growth factors and other cytokine-related proteins.
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Hot Cytokines
Immune Checkpoint Proteins
Immune checkpoints are regulators of immune activation. They consist of stimulatory and inhibitory pathways that maintain self-tolerance and assist with immune responses. Stimulatory immune checkpoints augment immunological responses against pathogens, while inhibitory immune checkpoints negatively regulate T-cell activation. In cancer, immune checkpoint mechanisms are often activated to suppress the nascent anti-tumor immune response. Key targets for cancer immunotherapy include PD-1, PD-L1, CTLA-4, CD28, and OX40.
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Hot Immune Checkpoint Proteins
Virus Proteins
Elabscience® is committed to providing solutions and services to support researchers in the study of infectious diseases, including SARS-CoV-2, SARS, MERS, HIV, HPV, and others. Recombinant antigens are a key component in infectious disease research. Elabscience's viral proteins include a variety of high-quality recombinant proteins expressed primarily in insect and mammalian cells, all of which undergo rigorous testing for purity and biological activity.
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●Human Coronavirus Antigens
SARS-CoV-2
SARS-CoV-2 structural proteins have important functions in pathogenesis as well as infectious virus assembly. These include the Spike protein (S), the Envelope protein (E), the Membrane protein (M), and the Nucleocapsid protein (N). Non-structural proteins form a large replication/transcription complex that is responsible for the replication and transcription of the virus genome and subgenomes.
SARS
SARS is Severe Acute Respiratory Syndrome, caused by SARS-CoV. SARS-CoV belongs to the betacoronavirus genus. The genome of SARS-CoV encodes structural proteins such as spike (S), envelope (E), membrane (M), and nucleocapsid (N) proteins, as well as non-structural proteins including papain-like protease (PLpro), chymotrypsin-like protease (3CLpro), RNA-dependent RNA polymerase (RdRp), and helicase (Hel).
MERS
MERS is Middle East Respiratory Syndrome, also known as camel flu, caused by a lethal zoonotic virus called MERS-CoV. The genome of MERS-CoV encodes structural proteins, including spike (S), membrane (M), nucleocapsid (N), and envelope (E), as well as various accessory proteins such as 3, 4a, 4b, 5, and 8b.
●Hot Viral Antigens
Hot Virus Proteins
- Influenza B Nucleoprotein Protein
- SARS-CoV-2 Helicase Protein
- SARS-CoV-2 Spike1 Protein
- HCoV-229E Spike1+spike2 Protein
- SARS-CoV-2 Papain-like Protease
- SARS-CoV-2 Spike1+spike2 Protein
- HCoV-229E Spike1 Protein
- SARS-CoV-2 Spike RBD Protein
- SARS-CoV-2 Spike Trimer Protein
- MERS-CoV S-trimer Protein
- SARS-CoV-2 Envelope Protein
- Enterovirus VP1 Protein
Custom Recombinant Protein Services
Elabscience's custom recombinant protein services provide a comprehensive portfolio of protein expression systems, including bacteria, yeast, baculovirus-infected insect cells, and mammalian cells. We offer the ideal level of protein purity for your downstream applications. With customized solutions, flexible production scales, and proprietary technologies, we partner with our clients to ensure efficient and high-quality reagent protein production, process development, and scale-up production of biologics for research purposes.
Features
Publications
Elabscience® products have been cited in over 16,000 papers published in SCI journals, with a total impact factor exceeding 58,000 for those papers using our products. Our products are featured in many top journals in biological research, such as Nature Medicine, Nature, Cell, Immunity, Molecular Cancer, Circulation, Advanced Materials and others.
Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis
IF ：20.479
Journal : NATURE IMMUNOLOGY(2020)
DOI : 10.1038/s41590-020-0673-x
PMID : 32424365
Products：HMGB1
