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ABI1 Polyclonal Antibody

Cat:E-AB-12222
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human gastric cancer,Human brain
Dilution

IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human ABI1
Abbre ABI1
Synonyms Abelson interactor 1;Abi-1;Abi1;ABI1;Abl binding protein 4;Abl interactor 1;Abl interactor protein 1;Abl-binding protein 4;AblBP4;e3B1;Eps8 binding protein;Eps8 SH3 domain binding protein;Eps8 SH3 domain-binding protein;Eps8-binding protein;Hssh3bp1;Interactor protein AblBP4;NAP1;Nap1 binding protein;Nap1-binding protein;Nap1BP;Spectrin SH3 domain binding protein 1;Spectrin SH3 domain-binding protein 1;SSH3BP
Swissprot
Cellular Localization Cytoplasm. Nucleus. Cell projection>lamellipodium. Cell projection>filopodium. Cell projection>growth cone. Cell junction>synapse>synaptosome. Cytoplasm>cytoskeleton. Localized to protruding lamellipodia and filopodia tips. Also localized to neuronal growth cones and synaptosomes.
Concentration 0.5 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cell Biology; Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14