ABI3BP Polyclonal Antibody

Uniprot : Q7Z7G0
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14758

      Synonyms:ABI gene family member 3 (NESH) binding protein,ABI gene family member 3 binding protein,ABI gene family member 3-binding protein,ABI3BP,FLJ41743,FLJ41754,Nesh binding protein,Nesh BP,Nesh-binding protein,NeshBP,Target of Nesh SH3,Target of Nesh-SH3,Tarsh,TARSH

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms ABI gene family member 3 (NESH) binding protein,ABI gene family member 3 binding protein,ABI gene family member 3-binding protein,ABI3BP,FLJ41743,FLJ41754,Nesh binding protein,Nesh BP,Nesh-binding protein,NeshBP,Target of Nesh SH3,Target of Nesh-SH3,Tarsh,TARSH
      Swissprot Q7Z7G0
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human ABI3BP
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.9 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted.
      Tissue specificity Expressed in brain, heart, lung, liver, pancreas kidney and placenta.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.

      Images

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ABI3BP Polyclonal Antibody at dilution 1:50

      Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using ABI3BP Polyclonal Antibody at dilution 1:50

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