ACE2 Polyclonal Antibody

Uniprot : Q9BYF1
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-12224

      Synonyms:ACE 2,ACE related carboxypeptidase,ACE-related carboxypeptidase,ACE2,ACE2,ACEH,Angiotensin converting enzyme 2,Angiotensin converting enzyme homolog,Angiotensin converting enzyme like protein,Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2,Angiotensin I converting enzyme 2,Angiotensin-converting enzyme homolog,DKFZP434A014,EC 3.4.17,metalloprotease MPROT 15,Metalloprotease MPROT15,OTTHUMP00000022963,Processed angiotensin-converting enzyme 2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms ACE 2,ACE related carboxypeptidase,ACE-related carboxypeptidase,ACE2,ACE2,ACEH,Angiotensin converting enzyme 2,Angiotensin converting enzyme homolog,Angiotensin converting enzyme like protein,Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2,Angiotensin I converting enzyme 2,Angiotensin-converting enzyme homolog,DKFZP434A014,EC 3.4.17,metalloprotease MPROT 15,Metalloprotease MPROT15,OTTHUMP00000022963,Processed angiotensin-converting enzyme 2
      Swissprot Q9BYF1
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthetic peptide of human ACE2
      Application IHC(Detection kit: E-IR-R217),ELISA
      Recommended dilution IHC 1:100-1:300
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted and Cell membrane.
      Tissue specificity Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

      Images

      Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ACE2 Polyclonal Antibody at dilution 1:200

      Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ACE2 Polyclonal Antibody at dilution 1:200

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      MSDS for ELISA

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