Purified Anti-Human CD41 Antibody[HIP8], Functional Grade (E-AB-F10880)
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For research use only.
| Alternate Names | HPA, PPP1R, ITGA2B, BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, PPP1R93, GPalpha Iib, Integrin alpha-Iib, Platelet membrane glycoprotein Iib, ITGAB, &, alpha-IIb integrin-n, BDPLT16, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, alpha subunit, antigen CD41, antigen CD41), form 2, Integrin, Integrin alpha 2b, Integrin alpha IIb, Integrin alpha-IIb light chain, integrin αⅡbβ3, ITA2B, platelet fibrinogen receptor, platelet glycoprotein IIb of IIb/IIIa complex, platelet specific antigen BAK |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood platelets |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells);Block Reported in the literaturee |
| Background | CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Human CD41 protein |
| Abbre | CD41 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Applications |
FCM;Block
|
| Research Areas | Cardiovascular;Immunology;Signal Transduction;Stem Cells |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | McCarty OJT, et al. Blood. 2000 Jul;96(5):1789-1794. |
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