Purified Anti-Human CD80 Antibody[2D10], Functional Grade (E-AB-F12320)
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For research use only.
| Alternate Names | LAB, CTLA-4 counter-receptor B, T-lymphocyte activation antigen CD, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7, CD80, CD28LGB7-1 antigen, T-lymphocyte activation antigen CD80, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1, B7-1, BB1, B lymphocyte activation antigen B7, B7-1 antigen, B7-1 antigen), CD28 antigen ligand 1, CD80 antigen, CD80 antigen (CD28 antigen ligand 1, CD80 molecule, Costimulatory factor CD80, costimulatory molecule variant IgV-CD80 |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Raji |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20‑100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Human CD80 protein |
| Abbre | CD80 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Applications |
FCM
|
| Research Areas | Immunology;Stem Cells |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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