Purified Anti-Human IL-4 Antibody[MP4-25D2], Functional Grade (E-AB-F12030)
![Purified Anti-Human IL-4 Antibody[MP4-25D2], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
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For research use only.
| Alternate Names | B-cell IgG differentiation factor, B-cell growth factor 1, BSF-1, IGG1 induction factor, IL-4, Interleukin-4 |
| Clone | |
| Leadtime | Order now, ship in 3 days |
| Background | IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Abbre | IL-4 |
| Swissprot | |
| Host | Rat |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rat IgG1, κ |
| Isotype Control | Purified Rat IgG1, κ Isotype Control[HRPN], Functional Grade |
| Applications |
FCM;Neut
|
| Research Areas | Immunology |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | Hiroko Nakatsukasa, et al. Nat Immunol. 2015 Oct;16(10):1077-84. |
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