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Cat.No.:E-AB-F1146L
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Alternate Names | Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b |
Swissprot | P11215 |
References |
1. Stewart M, et al. 1995. Curr. Opin. Cell Biol. 7:690.
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Form | Liquid |
Clone No. | ICRF44 |
Host | Mouse |
Isotype | Mouse IgG1, κ |
Isotype Control | Elab Fluor® 488 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792L] |
Reactivity | Human |
Application | FCM |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Recommended Use | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Shipping | Biological ice pack at 4℃ |
Stability & Storage | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Conjugation | Elab Fluor® 488 |
Elab Fluor® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter). | |
How to select the appropriate detection channel through the spectrogram?
CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X. |
Related Protocols | Staining Cell Surface Targets for Flow Cytometry |
Troubleshooting |
Product Name | Sizes | Price |
FITC Anti-Human CD11b Antibody[ICRF44] | 20Tests, 100Tests, 100Tests×2 | Check More |
PE Anti-Human CD11b Antibody[ICRF44] | 20Tests, 100Tests, 100Tests×2 | Check More |
APC Anti-Human CD11b Antibody[ICRF44] | 20Tests, 100Tests, 100Tests×2 | Check More |
PerCP Anti-Human CD11b Antibody[ICRF44] | 20Tests, 100Tests, 100Tests×2 | Check More |
PE/Cyanine5 Anti-Human CD11b Antibody[ICRF44] | 20Tests, 100Tests, 100Tests×2 | Check More |
PE/Cyanine7 Anti-Human CD11b Antibody[ICRF44] | 20Tests, 100Tests, 100Tests×2 | Check More |
PE/Cyanine5.5 Anti-Human CD11b Antibody[ICRF44] | 20Tests, 100Tests, 100Tests×2 | Check More |
PerCP/Cyanine5.5 Anti-Human CD11b Antibody[ICRF44] | 20Tests, 100Tests, 100Tests×2 | Check More |
Elab Fluor® 647 Anti-Human CD11b Antibody[ICRF44] | 20Tests, 100Tests, 100Tests×2 | Check More |
Elab Fluor® Red 780 Anti-Human CD11b Antibody[ICRF44] | 20Tests, 100Tests, 100Tests×2 | Check More |