Elab Fluor^® 488 Anti-Human CD32 Antibody[IV-3] (E-AB-F1075L)

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Size	Price	Qty
100Tests	$ 285.00	- +
20Tests	$ 115.00	- +
100Tests×2	$ 425.00	- +

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Isotype	Mouse IgG2b, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Abbre	CD32
Synonyms	IGFR2, CD32, CDw32, FCG2, FCGR2B, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, IgG Fc receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-b
Swissprot	P31994
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology, Innate Immunity
Clone No.	IV-3
Conjugation	Elab Fluor^®488
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).