Alternate Names	Complement receptor type 1,CR1,C3b/C4b receptor,CD35,CR1,C3BR
Swissprot	P17927
References	1. Zola Heddy, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules:The CD markers. WILEY-LISS. 2. Klickstein LB, et al. 1988. J. Exp. Med. 168:1699.

Product Details

Form	Liquid
Clone No.	E11(See Other Available Formats)
Host	Mouse
Isotype	Mouse IgG1, κ
Isotype Control	Elab Fluor^® 647 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792M]
Reactivity	Human
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Elab Fluor^® 647
	Elab Fluor^® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter).

How to select the appropriate detection channel through the spectrogram?

Background

CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
Purified Anti-Human CD35 Antibody[E11]	25μg, 100μg	Check More
Biotin Anti-Human CD35 Antibody[E11]	25μg, 100μg	Check More
FITC Anti-Human CD35 Antibody[E11]	20Tests, 100Tests, 100Tests×2	Check More
PE Anti-Human CD35 Antibody[E11]	20Tests, 100Tests, 100Tests×2	Check More
APC Anti-Human CD35 Antibody[E11]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5 Anti-Human CD35 Antibody[E11]	20Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Human CD35 Antibody[E11]	20Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 488 Anti-Human CD35 Antibody[E11]	20Tests, 100Tests, 100Tests×2	Check More
PE/Elab Fluor^® 594 Anti-Human CD35 Antibody[E11]	20Tests, 100Tests, 100Tests×2	Check More

Citations

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