AF/LE Purified Anti-Human IL-4 Antibody[MP4-25D2] (E-AB-F12030)
![AF/LE Purified Anti-Human IL-4 Antibody[MP4-25D2] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: None (AF/LE)
APC Elab Fluor®700 FITC None (AF/LE) PE PE/Elab Fluor®594 Unconjugated Show More
| Isotype | Rat IgG1, κ |
| Host | Rat |
| Reactivity | Human |
| Applications | ICFCM, Neut |
| Clonality | Monoclonal |
| Abbre | IL-4 |
| Synonyms | B-cell IgG differentiation factor, B-cell growth factor 1, BSF-1, IGG1 induction factor, IL-4, Interleukin-4 |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Research Areas | Immunology |
| Clone No. | MP4-25D2 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells. |
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