|Alternate Names||Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119|
1. Basu M, et al. 1988. P. Natl. Acad. Sci. USA 85:6282.
2. Codias EK, et al. 1990. J. Immunol. 144:2197.
|Clone No.||GR-20(See Other Available Formats)|
|Isotype||Rat IgG2a, κ|
|Isotype Control||AF/LE Purified Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F098330]|
|Application||FCM (See the Application Description)|
|Storage Buffer||0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.|
|Recommended Use||Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.|
|Shipping||Biological ice pack at 4℃|
|Stability & Storage||Keep as concentrated solution.
Store at 2~8℃. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
|Conjugation||None (Purified antibody/Azide Free/Low endotoxin)|
|CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.|
|Related Protocols||Staining Cell Surface Targets for Flow Cytometry|
|E-AB-F11150||AF/LE Purified Anti-Mouse CD119 Antibody[GR-20] E-AB-F11150||50 μg, 500 μg, 1 mg|
|E-AB-F1115A||Purified Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115A||50 μg, 100 μg|
|E-AB-F1115B||Biotin Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115B||50 μg, 100 μg|
|E-AB-F1115D||PE Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115D||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1115E||APC Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115E||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1115UD||PE Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115UD||25μg, 50μg, 100μg|
|E-AB-F1115UE||APC Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115UE||25μg, 50μg, 100μg|
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