AF/LE Purified Anti-Mouse CD119 Antibody[GR-20] E-AB-F11150

Uniprot : P15261
  • Host: Rat
  • Applications: FCM
  • Isotype: Rat IgG2a, κ

To Purchase E-AB-F11150

Size:
  • 50 μg
  • 500 μg
  • 1 mg
Price: $75
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Antigen Details

Alternate Names Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119
Swissprot P15261
References
1. Basu M, et al. 1988. P. Natl. Acad. Sci. USA 85:6282.
2. Codias EK, et al. 1990. J. Immunol. 144:2197.

Product Details

Form Liquid
Clone No. GR-20(See Other Available Formats)
Host Rat
Isotype Rat IgG2a, κ
Isotype Control AF/LE Purified Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F098330]
Reactivity Mouse
Application FCM (See the Application Description)
Storage Buffer 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 g per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation None (Purified antibody/Azide Free/Low endotoxin)

Background

CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F11150 AF/LE Purified Anti-Mouse CD119 Antibody[GR-20] E-AB-F11150 50 μg, 500 μg, 1 mg
E-AB-F1115A Purified Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115A 50 μg, 100 μg
E-AB-F1115B Biotin Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115B 50 μg, 100 μg
E-AB-F1115D PE Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115D 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1115E APC Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115E 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1115UD PE Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115UD 25μg, 50μg, 100μg
E-AB-F1115UE APC Anti-Mouse CD119 Antibody[GR-20] E-AB-F1115UE 25μg, 50μg, 100μg

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