AF/LE Purified Anti-Mouse CD120b Antibody[TR75-54.7] E-AB-F10350

Uniprot : P25119
  • Host: Armenian Hamster
  • Applications: FCM,WB,Block,IP
  • Isotype: Armenian Hamster IgG

To Purchase E-AB-F10350

Size:
  • 50 μg
  • 500 μg
  • 1 mg
Price: $95
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Antigen Details

Alternate Names Tumor necrosis factor receptor superfamily member 1B,Tnfrsf1b,Tumor necrosis factor receptor 2,TNF-R2,TNF-RII,TNFR-II,p75,p80 TNF-alpha receptor,CD120b
Swissprot P25119
References
1. Aggarwal BB, et al. 1985. Nature 318 665.
2. Chan FKM, et al. 2000. Science 288:2351.
3. Loetscher H, et al. 1990. Cell 61:351.
4. Rothe J, et al. 1993. Nature 364:798.

Product Details

Form Liquid
Clone No. TR75-54.7(See Other Available Formats)
Host Armenian Hamster
Isotype Armenian Hamster IgG
Isotype Control AF/LE Purified Armenian Hamster IgG Isotype Control[PIP] [Product E-AB-F098530]
Reactivity Mouse
Application FCM,WB,Block,IP (See the Application Description)
Storage Buffer 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 g per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation None (Purified antibody/Azide Free/Low endotoxin)

Background

CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F10350 AF/LE Purified Anti-Mouse CD120b Antibody[TR75-54.7] E-AB-F10350 50 μg, 500 μg, 1 mg
E-AB-F1035A Purified Anti-Mouse CD120b Antibody[TR75-54.7] E-AB-F1035A 50 μg, 100 μg
E-AB-F1035B Biotin Anti-Mouse CD120b Antibody[TR75-54.7] E-AB-F1035B 50 μg, 100 μg
E-AB-F1035D PE Anti-Mouse CD120b Antibody[TR75-54.7] E-AB-F1035D 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1035UD PE Anti-Mouse CD120b Antibody[TR75-54.7] E-AB-F1035UD 25 μg, 50 μg, 100 μg, 200 μg

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