AF/LE Purified Anti-Mouse CD122/IL-2RB Antibody[5H4] (E-AB-F10290)
![AF/LE Purified Anti-Mouse CD122/IL-2RB Antibody[5H4] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
| Alternate Names | IL-2R subunit beta, CD122, High affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2RB, Il2rb, Interleukin-2 receptor subunit beta, p70-75 |
| Clone No | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(1×105-5×105 cells) |
| Background | CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
| Immunogen | Recombinant Mouse CD122 protein |
| Abbre | CD122 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rat IgG2a, κ |
| Applications |
FCM
|
| Research Areas | Immunology |
| Cellular Localization |
Cell membrane, Cell surface
|
| Tissue Specificity |
Expressed in peripheral lymph node and 57 other cell types or tissues
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®700
Elab Fluor®Violet 450
FITC
None (AF/LE)
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PerCP/Cyanine 5.5
Unconjugated
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