FITC Anti-Mouse CD122/IL-2RB Antibody[5H4] (E-AB-F1029C)

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Cell Markers

Size	Price	Qty
100Tests	$ 57.00	- +
50Tests	$ 32.00	- +
100Tests×2	$ 100.00	- +

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Conjugation: FITC

Isotype	Rat IgG2a, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Isotype Control	FITC Rat IgG2a, κ Isotype Control[2A3]
Abbre	CD122
Synonyms	IL-2R subunit beta, CD122, High affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2RB, Il2rb, Interleukin-2 receptor subunit beta, p70-75
Swissprot	P16297
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology
Clone No.	5H4
Conjugation	FITC
Conjugation Information	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.