AF/LE Purified Anti-Mouse CD132 Antibody[3E12] E-AB-F10150

Uniprot : P34902
  • Host: Rat
  • Applications: FCM,IP
  • Isotype: Rat IgG2b, κ

To Purchase E-AB-F10150

Size:
  • 50 μg
  • 500 μg
  • 1 mg
Price: $95
Qty:

Antigen Details

Alternate Names Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132
Swissprot P34902
References
1. Itano M, et al. 1996. Tohoku J. Exp. Med. 178:389.
2. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication .
3. Nakarai T, et al. 1994. J. Exp. Med. 180:241.
4. Kawahara A, et al. 1995. Proc. Natl. Acad. Sci. USA. 92:8724.
5. Habib T, et al. 2002. Biochemistry. 41:8725.
6. Matthews DJ, et al. 1995. Blood 85:38.

Product Details

Form Liquid
Clone No. 3E12(See Other Available Formats)
Host Rat
Isotype Rat IgG2b, κ
Isotype Control AF/LE Purified Rat IgG2b, κ Isotype Control[LTF-2] [Product E-AB-F098430]
Reactivity Mouse
Application FCM,IP (See the Application Description)
Storage Buffer 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 g per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation None (Purified antibody/Azide Free/Low endotoxin)

Background

CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F10150 AF/LE Purified Anti-Mouse CD132 Antibody[3E12] E-AB-F10150 50 μg, 500 μg, 1 mg
E-AB-F1015A Purified Anti-Mouse CD132 Antibody[3E12] E-AB-F1015A 50 μg, 100 μg
E-AB-F1015B Biotin Anti-Mouse CD132 Antibody[3E12] E-AB-F1015B 50 μg, 100 μg
E-AB-F1015D PE Anti-Mouse CD132 Antibody[3E12] E-AB-F1015D 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1015E APC Anti-Mouse CD132 Antibody[3E12] E-AB-F1015E 20 Tests, 50 Tests, 100 Tests
E-AB-F1015UD PE Anti-Mouse CD132 Antibody[3E12] E-AB-F1015UD 25 μg, 50 μg, 100 μg, 200 μg
E-AB-F1015UE APC Anti-Mouse CD132 Antibody[3E12] E-AB-F1015UE 25 μg, 50 μg, 100 μg, 200 μg

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