Current Position:Home>>Antibodies>>Flow Cytometry Antibodies>> AF/LE Purified Anti-Mouse CD209b Antibody[22D1] E-AB-F10220
Cat.No.:E-AB-F10220
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Alternate Names | CD209 antigen-like protein B,Cd209b,DC-SIGN-related protein 1,DC-SIGNR1,OtB7,CD209,Cd209b |
Swissprot | Q8CJ91 |
References |
1. Zhou Y, et al. 2010. Nat. Med. 16:1128.
2. Saunders SP, et al. 2010. J. Immunol. 184:2627. 3. Silva-Martin N, et al. 2009. Acta. Crystallogr. Sect. F. Struct. Biol. Cryst. Commun. 65:1264. 4. Saunders SP, et al. 2009. Infect. Immun. 77:399. 5. Park JY, et al. 2009. Neurosci. Lett. 450:246. 6. Lanoue A, et al. J. Exp. Med. 200:1383. |
Form | Liquid |
Clone No. | 22D1(See Other Available Formats) |
Host | Armenian Hamster |
Isotype | Armenian Hamster IgG |
Isotype Control | AF/LE Purified Armenian Hamster IgG Isotype Control[PIP] [Product E-AB-F098530] |
Reactivity | Mouse |
Application | FCM (See the Application Description) |
Storage Buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
Recommended Use | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Shipping | Biological ice pack at 4℃ |
Stability & Storage | Keep as concentrated solution. Store at 2~8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Conjugation | None (Purified antibody-Azide Free/Low endotoxin) |
How to select the appropriate detection channel through the spectrogram?
CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway. |
Related Protocols | Staining Cell Surface Targets for Flow Cytometry |
Troubleshooting |
Product Name | Sizes | Price |
Purified Anti-Mouse CD209b Antibody[22D1] E-AB-F1022A | 25μg, 100μg | Check More |
Biotin Anti-Mouse CD209b Antibody[22D1] E-AB-F1022B | 25μg, 100μg | Check More |
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