For research use only.
| Background | CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Alternate Names | Activation B7-1 antigen, B7, Cd80, T-lymphocyte activation antigen CD80 |
| Swissprot | |
| Clone No | |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Isotype | Armenian Hamster IgG |
| Application |
FCM;Block
|
| Conjugation | Unconjugated |
| Storage Buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Expiration date | 12 months |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®Red 780
Elab Fluor®Violet 450
Elab Fluor®Violet 610
FITC
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP/Cyanine 5.5
Unconjugated
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