AF/LE Purified Anti-Mouse CD80 Antibody[16-10A1] (E-AB-F09920)
![AF/LE Purified Anti-Mouse CD80 Antibody[16-10A1] - 1](http://file.elabscience.com/assets/images/loading.png)
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For research use only.
| Isotype | Armenian Hamster IgG |
| Host | Armenian Hamster |
| Reactivity | Mouse |
| Applications | FCM, Block |
| Clonality | Monoclonal |
| Abbre | CD80 |
| Synonyms | Activation B7-1 antigen, B7, Cd80, T-lymphocyte activation antigen CD80 |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Research Areas | Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers |
| Clone No. | 16-10A1 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
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