For research use only.
| Background | CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Alternate Names | Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86 |
| Swissprot | |
| Clone No | |
| Host | Rat |
| Reactivity | Mouse |
| Isotype | Rat IgG2a, κ |
| Application |
FCM
|
| Conjugation | Unconjugated |
| Storage Buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Expiration date | 12 months |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Other Clones
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Other Formats
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APC
Biotin
Elab Fluor®488
Elab Fluor®647
Elab Fluor®Red 780
Elab Fluor®Violet 610
FITC
PE
PE/Cyanine 5
PE/Cyanine 5.5
PE/Cyanine 7
PE/Elab Fluor®594
PerCP/Cyanine 5.5
Unconjugated
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