AF/LE Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F11240

  • Host: Armenian Hamster
  • Applications: FCM,IP,IHC
  • Isotype: Armenian Hamster IgG

To Purchase E-AB-F11240

Size:
  • 50 μg
  • 500 μg
  • 1 mg
Price: $75
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Antigen Details

Alternate Names TCR-γ/δ, γ/δ TCR
References
1. Skarstein K, et al. 1995. Immunology 81:497.
2. Harrison LC, et al. 1996. J. Exp. Med. 184:2167.
3. Wildner G, et al. 1996. Eur. J. Immunol. 26:2140.
4. Brandes M, et al. 2005. Science 309:264.

Product Details

Form Liquid
Clone No. UC7-13D5(See Other Available Formats)
Host Armenian Hamster
Isotype Armenian Hamster IgG
Isotype Control AF/LE Purified Armenian Hamster IgG Isotype Control[PIP] [Product E-AB-F098530]
Reactivity Mouse
Application FCM,IP,IHC (See the Application Description)
Storage Buffer 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 g per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation None (Purified antibody/Azide Free/Low endotoxin)

Background

T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F11240 AF/LE Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F11240 50 μg, 500 μg, 1 mg
E-AB-F1124A Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124A 50 μg, 100 μg
E-AB-F1124B Biotin Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124B 50 μg, 100 μg
E-AB-F1124C FITC Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124C 50 Tests, 100 Tests, 500 Tests
E-AB-F1124D PE Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124D 50 Tests, 100 Tests, 500 Tests
E-AB-F1124E APC Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124E 50 Tests, 100 Tests, 500 Tests
E-AB-F1124UC FITC Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124UC 25 μg, 50 μg, 100 μg, 200 μg
E-AB-F1124UD PE Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124UD 25 μg, 50 μg, 100 μg, 200 μg
E-AB-F1124UE APC Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124UE 25μg, 50μg, 100μg

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