|Alternate Names||TCR-γ/δ, γ/δ TCR|
1. Skarstein K, et al. 1995. Immunology 81:497.
2. Harrison LC, et al. 1996. J. Exp. Med. 184:2167.
3. Wildner G, et al. 1996. Eur. J. Immunol. 26:2140.
4. Brandes M, et al. 2005. Science 309:264.
|Clone No.||UC7-13D5(See Other Available Formats)|
|Isotype||Armenian Hamster IgG|
|Isotype Control||AF/LE Purified Armenian Hamster IgG Isotype Control[PIP] [Product E-AB-F098530]|
|Application||FCM (See the Application Description)|
|Storage Buffer||0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.|
|Recommended Use||Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 106 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.|
|Shipping||Biological ice pack at 4℃|
|Stability & Storage||Keep as concentrated solution.
Store at 2~8℃. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
|Conjugation||None (Purified antibody/Azide Free/Low endotoxin)|
|T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo.|
|Related Protocols||Staining Cell Surface Targets for Flow Cytometry|
|E-AB-F11240||AF/LE Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F11240||50 μg, 500 μg, 1 mg|
|E-AB-F1124A||Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124A||50 μg, 100 μg|
|E-AB-F1124B||Biotin Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124B||50 μg, 100 μg|
|E-AB-F1124C||FITC Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124C||50 Tests, 100 Tests, 500 Tests|
|E-AB-F1124D||PE Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124D||50 Tests, 100 Tests, 500 Tests|
|E-AB-F1124E||APC Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124E||50 Tests, 100 Tests, 500 Tests|
|E-AB-F1124UC||FITC Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124UC||25 μg, 50 μg, 100 μg, 200 μg|
|E-AB-F1124UD||PE Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124UD||25 μg, 50 μg, 100 μg, 200 μg|
|E-AB-F1124UE||APC Anti-Mouse TCR γ/δ Antibody[UC7-13D5] E-AB-F1124UE||25μg, 50μg, 100μg|
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