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For research use only.

Verified Samples Verified Samples in IF: HeLa
Dilution IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human ALAD (NP_000022.3).
Abbre ALAD
Synonyms ALAD,  ALADH,  PBGS
Swissprot
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cell Biology,  Cardiovascular
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
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Unconjugated

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