ALDH4A1 Polyclonal Antibody

Uniprot : P30038
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14536

      Synonyms:AL4A1,aldehyde dehydrogenase 4,aldehyde dehydrogenase 4 family,member A1,Aldehyde dehydrogenase family 4 member A1,Aldehyde dehydrogenase,family 4,subfamily A,member 1,ALDH4,aldh4a1,Delta 1 pyrroline 5 carboxylate dehydrogenase,mitochondrial,Delta-1-pyrroline-5-carboxylate dehydrogenase,L-glutamate gamma-semialdehyde dehydrogenase,mitochondrial,mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase,P5C dehydrogenase,P5CD,P5CDh,P5CDhL,P5CDhS,Pyrroline-5-carboxylate dehydrogenase,RP11 128M10.1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AL4A1,aldehyde dehydrogenase 4,aldehyde dehydrogenase 4 family,member A1,Aldehyde dehydrogenase family 4 member A1,Aldehyde dehydrogenase,family 4,subfamily A,member 1,ALDH4,aldh4a1,Delta 1 pyrroline 5 carboxylate dehydrogenase,mitochondrial,Delta-1-pyrroline-5-carboxylate dehydrogenase,L-glutamate gamma-semialdehyde dehydrogenase,mitochondrial,mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase,P5C dehydrogenase,P5CD,P5CDh,P5CDhL,P5CDhS,Pyrroline-5-carboxylate dehydrogenase,RP11 128M10.1
      Swissprot P30038
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human ALDH4A1
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Mitochondrion matrix.
      Tissue specificity Highest expression is found in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

      Images

      Western Blot analysis of Human fetal liver tissue using ALDH4A1 Polyclonal Antibody at dilution of 1:350

      Immunohistochemistry of paraffin-embedded Human colon cancer using ALDH4A1 Polyclonal Antibody at dilution of 1:35

      Immunohistochemistry of paraffin-embedded Human breast cancer using ALDH4A1 Polyclonal Antibody at dilution of 1:35

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