ALDH8A1 Polyclonal Antibody

Uniprot : Q9H2A2
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    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14538

      Synonyms:ALDH12,DJ352A20.2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms ALDH12,DJ352A20.2
      Swissprot Q9H2A2
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human ALDH8A1
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:1000-1:5000, IHC 1:50-1:200
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,Extracellular region or secreted,extracellular exosome,Other locations:intracellular
      Tissue specificity Highly expressed in adult kidney and liver. Detected at lower levels in fetal liver and kidney.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene.

      Images

      Western Blot analysis of Mouse liver and kidney tissue using ALDH8A1 Polyclonal Antibody at dilution of 1:800

      Immunohistochemistry of paraffin-embedded Human liver cancer using ALDH8A1 Polyclonal Antibody at dilution of 1:40

      Immunohistochemistry of paraffin-embedded Human brain using ALDH8A1 Polyclonal Antibody at dilution of 1:40

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