ALKBH2 Polyclonal Antibody

Uniprot : Q6NS38
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14464

      Synonyms:2OG Fe(II) oxy DC1,9530023G02,ABH 2,ABH2,alkB alkylation repair homolog 2,ALKB2,ALKBH2 alkB,ALKBH2,Alkylated DNA repair protein alkB homolog,Alkylated DNA repair protein alkB homolog 2,Alkylation repair homolog 2,Alpha ketoglutarate dependent dioxygenase alkB homolog 2,Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2,AU016977,DNA oxidative demethylase ALKBH2,EC 1.14.11.,FLJ99103,hABH2,mABH2,MGC90512,Oxy DC1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 2OG Fe(II) oxy DC1,9530023G02,ABH 2,ABH2,alkB alkylation repair homolog 2,ALKB2,ALKBH2 alkB,ALKBH2,Alkylated DNA repair protein alkB homolog,Alkylated DNA repair protein alkB homolog 2,Alkylation repair homolog 2,Alpha ketoglutarate dependent dioxygenase alkB homolog 2,Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2,AU016977,DNA oxidative demethylase ALKBH2,EC 1.14.11.,FLJ99103,hABH2,mABH2,MGC90512,Oxy DC1
      Swissprot Q6NS38
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human ALKBH2
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:500-1:2000
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Detected in replication foci during S-phase.
      Tissue specificity Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

      Images

      Western Blot analysis of Human fetal liver and seminoma tissue, RAW264.7 cell using ALKBH2 Polyclonal Antibody at dilution of 1:650

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