AMIGO2 Polyclonal Antibody

Uniprot : Q86SJ2
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14557

      Synonyms:Adhesion molecule with Ig like domain 2,ALI 1,ALI1,Alivin 1,Alivin-1,Alivin1,AMGO2,AMIGO 2,AMIGO-2,Amigo2,Amphoterin induced gene 2,Amphoterin induced protein 2,Amphoterin-induced gene and open reading frame 2,Amphoterin-induced protein 2,DEGA,Differentially expressed in gastric adenocarcinoma,Differentially expressed in gastric adenocarcinomas,Transmembrane protein AMIGO 2,Transmembrane protein AMIGO2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Adhesion molecule with Ig like domain 2,ALI 1,ALI1,Alivin 1,Alivin-1,Alivin1,AMGO2,AMIGO 2,AMIGO-2,Amigo2,Amphoterin induced gene 2,Amphoterin induced protein 2,Amphoterin-induced gene and open reading frame 2,Amphoterin-induced protein 2,DEGA,Differentially expressed in gastric adenocarcinoma,Differentially expressed in gastric adenocarcinomas,Transmembrane protein AMIGO 2,Transmembrane protein AMIGO2
      Swissprot Q86SJ2
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human AMIGO2
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
      Concentration 0.6 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane. Nucleus. Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.
      Tissue specificity Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction

      Images

      Western Blot analysis of A172 cell using AMIGO2 Polyclonal Antibody at dilution of 1:597

      Immunohistochemistry of paraffin-embedded Human colon cancer using AMIGO2 Polyclonal Antibody at dilution of 1:50

      Immunohistochemistry of paraffin-embedded Human cervical cancer using AMIGO2 Polyclonal Antibody at dilution of 1:50

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