ANKMY2 Polyclonal Antibody

Uniprot : Q8IV38
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14569

      Synonyms:Ankmy2,ANKY2,Ankyrin repeat and MYND domain containing 2,Ankyrin repeat and MYND domain containing protein 2,Ankyrin repeat and MYND domain-containing protein 2,DKFZP564O043,OTTHUMP00000116019,OTTHUMP00000201684,ZMYND20

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Ankmy2,ANKY2,Ankyrin repeat and MYND domain containing 2,Ankyrin repeat and MYND domain containing protein 2,Ankyrin repeat and MYND domain-containing protein 2,DKFZP564O043,OTTHUMP00000116019,OTTHUMP00000201684,ZMYND20
      Swissprot Q8IV38
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human ANKMY2
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:100
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell projection>cilium.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states. 

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ANKMY2 Polyclonal Antibody at dilution 1:30

      Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ANKMY2 Polyclonal Antibody at dilution 1:30

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