AP2A1 Polyclonal Antibody

Uniprot : O95782
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-17662

      Synonyms:100 kDa coated vesicle protein A,Adapter-related protein complex 2 alpha-1 subunit,adapter-related protein complex 2 subunit alpha-1,Adaptin alpha A,Adaptin alpha,Adaptor protein complex AP 2 alpha 1 subunit,adaptor protein complex AP 2 subunit alpha 1,Adaptor protein complex AP-2 subunit alpha-1,Adaptor protein complex AP2 alpha 1 subunit,adaptor protein complex AP2 subunit alpha 1,Adaptor related protein complex 2 alpha 1 subunit,Adaptor related protein complex AP 2 alpha 1 subunit,Adaptor related protein complex AP2 alpha 1 subunit,ADTAA,Alpha A adaptin,Alpha adaptin A,Alpha-adaptin A,alpha1 adaptin,Alpha1-adaptin,AP 2 alpha,AP 2 complex subunit alpha 1,AP-2 complex subunit alpha-1,AP2 complex subunit alpha 1,AP2-ALPHA,Ap2a1,AP2A1,CLAPA 1,CLAPA1,Clathrin adaptor complex AP2. alpha subunit,Clathrin assembly protein complex 2 alpha A large chain,Clathrin assembly protein complex 2 alpha-A large chain,Clathrin associated / assembly / adaptor protein large alpha 1,clathrin associated assembly adaptor protein large alpha 1,clathrin associated/assembly/adaptor protein,large,alpha 1,Plasma membrane adaptor HA 2/AP 2 adaptin alpha A subunit,Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 100 kDa coated vesicle protein A,Adapter-related protein complex 2 alpha-1 subunit,adapter-related protein complex 2 subunit alpha-1,Adaptin alpha A,Adaptin alpha,Adaptor protein complex AP 2 alpha 1 subunit,adaptor protein complex AP 2 subunit alpha 1,Adaptor protein complex AP-2 subunit alpha-1,Adaptor protein complex AP2 alpha 1 subunit,adaptor protein complex AP2 subunit alpha 1,Adaptor related protein complex 2 alpha 1 subunit,Adaptor related protein complex AP 2 alpha 1 subunit,Adaptor related protein complex AP2 alpha 1 subunit,ADTAA,Alpha A adaptin,Alpha adaptin A,Alpha-adaptin A,alpha1 adaptin,Alpha1-adaptin,AP 2 alpha,AP 2 complex subunit alpha 1,AP-2 complex subunit alpha-1,AP2 complex subunit alpha 1,AP2-ALPHA,Ap2a1,AP2A1,CLAPA 1,CLAPA1,Clathrin adaptor complex AP2. alpha subunit,Clathrin assembly protein complex 2 alpha A large chain,Clathrin assembly protein complex 2 alpha-A large chain,Clathrin associated / assembly / adaptor protein large alpha 1,clathrin associated assembly adaptor protein large alpha 1,clathrin associated/assembly/adaptor protein,large,alpha 1,Plasma membrane adaptor HA 2/AP 2 adaptin alpha A subunit,Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit
      Swissprot O95782
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthetic peptide of human AP2A1
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-2000, IHC 1:25-100, ELISA 1:2000-5000
      Concentration 0.6 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane. Membrane>coated pit. AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV.
      Tissue specificity Isoform A expressed in forebrain, skeletal muscle, spinal cord, cerebellum, salivary gland, heart and colon. Isoform B is widely expressed in tissues and also in breast cancer and in prostate carcinoma cells.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms.

      Images

      Immunohistochemistry of paraffin-embedded Human liver cancer using AP2A1 Polyclonal Antibody at dilution of 1/20

      Western Blot analysis of A431, 231 and NIH/3T3 cell using AP2A1 Polyclonal Antibody at dilution of 1/250

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