APC Anti-Human CD8a Antibody[OKT-8]

Uniprot : P01732
    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience
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    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience
    • Flow cytometry antibody-Elabscience

      Catalog number:E-AB-F1110E

      Synonyms:T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL

      Size:
      • 20 Tests
      • 50 Tests
      • 100 Tests
      • 200 Tests
      Qty:
      - +
      Price: $35

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual
      (See Other Available Formats)

      Antigen Information

      Alternate Names T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL
      Uniprot ID P01732
      Background CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

      Product Details

      Form Liquid
      Clone No. OKT-8 (See Other Available Formats)
      Host Mouse
      Isotype Mouse IgG2a, κ
      Isotype Control APC Mouse IgG2a, κ Isotype Control[C1.18.4] [Product E-AB-F09802E]
      Reactivity Human
      Application FCM (See the Application Description)
      Storage Buffer PBS with 0.05% Proclin300, 1% BSA
      Shipping Biological ice pack at 4 ℃
      Stability & Storage Keep as concentrated solution.
      Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
      Centrifuge before opening to ensure complete recovery of vial contents.
      This product is guaranteed up to one year from purchase.

      Fluorophore

      Conjugation: APC

      Recommended Use

      Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µl staining volume or per 100 µl of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

      Product Data

      • Human pheripheral blood cells are stained with APC Anti-Human CD8a Antibody(filled gray histogram). Unstained pheripheral blood cells (blank black histogram) are used as control.

      References

      1. Knapp W. W. Knapp .. et al.Oxford University Press; 1989; :1-1182.
      2. Reimann KA, Waite BC, Lee-Parritz DE, et al. Cytometry. 1994; 17(1):102-108.
      3. Roederer M, Kantor AB, Parks DR, Herzenberg LA. Cytometry. 1996; 24(3):191-197.
      4. Schlossman SF. Stuart F. Schlossman .. et al. Oxford University Press; 1995.
      5. Sopper S, Stahl-Hennig C, Demuth M, Johnston IC, Dorries R, ter Meulen V. Cytometry. 1997; 29(4):351-362.

      Additional Products

      Catalog No. Product Name Sizes
      E-AB-F11100 AF/LE Purified Anti-Human CD8a Antibody[OKT-8] 50 μg, 500 μg, 1 mg
      E-AB-F1110A Purified Anti-Human CD8a Antibody[OKT-8] 25 μg, 100 μg
      E-AB-F1110B Biotin Anti-Human CD8a Antibody[OKT-8] 25 μg, 100 μg
      E-AB-F1110C FITC Anti-Human CD8a Antibody[OKT-8] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1110D PE Anti-Human CD8a Antibody[OKT-8] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1110E APC Anti-Human CD8a Antibody[OKT-8] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1110F PerCP Anti-Human CD8a Antibody[OKT-8] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1110G PE/Cyanine5 Anti-Human CD8a Antibody[OKT-8] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1110H PE/Cyanine7 Anti-Human CD8a Antibody[OKT-8] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1110I PE/Cyanine5.5 Anti-Human CD8a Antibody[OKT-8] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1110J PerCP/Cyanine5.5 Anti-Human CD8a Antibody[OKT-8] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1110L AF488 Anti-Human CD8a Antibody[OKT-8] 20 Tests, 50 Tests, 100 Tests, 200 Tests
      E-AB-F1110M AF647 Anti-Human CD8a Antibody[OKT-8] 20 Tests, 50 Tests, 100 Tests, 200 Tests
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