APC Anti-Human/Mouse KLRG-1 Antibody[2F1] (E-AB-F1273UE)

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	100μg	$ 228.00	- +
	25μg	$ 70.00	- +

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Isotype	Syrian Hamster IgG
Host	Syrian Hamster
Reactivity	Human, Mouse
Applications	FCM
Clonality	Monoclonal
Abbre	KLRG-1
Synonyms	2F1-Ag, MAFA
Swissprot	Q96E93 O88713
Cellular Localization	Membrane
Concentration	0.2 mg/mL
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology
Clone No.	2F1
Conjugation	APC
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG22 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.