|Alternate Names||OX-2 membrane glycoprotein,OX-2, MRC|
1. Hoek RM, et al. 2000. Science 290:1768.
2. Gorczynski R, et al. 2004. J. of Immunol. 172:7744.
3. Gorczynski L, et al. 1999. J. Immunol. 162:774.
4. Rosenblum MD, et al. 2004. Blood 103:2691.
5. Zhang S, et al. 2004. J. of Immunol. 173:6786.
6. Barclay AN, et al. 2002. Trends Immunol. 23:285.
|Clone No.||OX-90(See Other Available Formats)|
|Isotype||Rat IgG2a, κ|
|Isotype Control||APC Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09832E]|
|Application||FCM (See the Application Description)|
|Storage Buffer||PBS with 0.05% Proclin300, 1% BSA|
|Recommended Use||Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.|
|Shipping||Biological ice pack at 4℃|
|Stability & Storage||Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
|CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, B cells, and brain tissue (neurons); but not on NK cells, granulocytes, monocytes, or macrophages. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. CD200 is the ligand for CD200 receptor (CD200R). The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.|
|Related Protocols||Staining Cell Surface Targets for Flow Cytometry|
|E-AB-F1234E||APC Anti-Mouse CD200 Antibody[OX-90] E-AB-F1234E||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1234H||PE/Cyanine7 Anti-Mouse CD200 Antibody[OX-90] E-AB-F1234H||20 Tests, 50 Tests, 100 Tests, 200 Tests|
|E-AB-F1234UE||APC Anti-Mouse CD200 Antibody[OX-90] E-AB-F1234UE||25 μg, 50 μg, 100 μg, 200 μg|
|E-AB-F1234UH||PE/Cyanine7 Anti-Mouse CD200 Antibody[OX-90] E-AB-F1234UH||25 μg, 50 μg, 100 μg, 200 μg|
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