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ARNTL Polyclonal Antibody

Cat:E-AB-11006
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: WB
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Product Details
Verified Samples Verified Samples in WB:Human fetal liver,Mouse stomach,Hela,HepG2
Dilution

WB 1:500-1:2000

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human ARNTL
Abbre ARNTL
Synonyms ARNT like protein 1 brain and muscle;Arntl;Aryl hydrocarbon receptor nuclear translocator like;Aryl hydrocarbon receptor nuclear translocator like protein 1;Aryl hydrocarbon receptor nuclear translocator-like protein 1;Basic helix loop helix PAS orphan MOP3;Basic helix loop helix PAS protein MOP3;Basic-helix-loop-helix-PAS protein MOP3;bHLH PAS protein JAP3;bHLH-PAS protein JAP3;bHLHe5;BMAL 1;BMAL1;BMAL1c;Brain and muscle ARNT like 1;Brain and muscle ARNT-like 1;CG8727 PA;Class E basic helix-loop-helix protein 5;cycle;JAP 3;JAP3;Member of PAS protein 3;Member of PAS superfamily 3;MGC47515;MOP 3;MOP3;PAS domain-containing protein 3;PASD 3;PASD3;TIC
Swissprot
Calculated MW 69kDa
Cellular Localization Nucleus. Cytoplasm. Nucleus, PML body. Shuttles between the nucleus and the cytoplasm and this nucleocytoplasmic shuttling is essential for the nuclear accumulation of CLOCK, target gene transcription and the degradation of the CLOCK-ARNTL/BMAL1 heterodimer. The sumoylated form localizes in the PML body. Sequestered to the cytoplasm in the presence of ID2.
Concentration 0.9 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.