ARNTL Polyclonal Antibody
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Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse;Rat
- Applications: WB
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Product Details
Verified Samples |
Verified Samples in WB:Human fetal liver,Mouse stomach,Hela,HepG2 |
Dilution |
WB 1:500-1:2000 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human ARNTL |
Abbre | ARNTL |
Synonyms | ARNT like protein 1 brain and muscle;Arntl;Aryl hydrocarbon receptor nuclear translocator like;Aryl hydrocarbon receptor nuclear translocator like protein 1;Aryl hydrocarbon receptor nuclear translocator-like protein 1;Basic helix loop helix PAS orphan MOP3;Basic helix loop helix PAS protein MOP3;Basic-helix-loop-helix-PAS protein MOP3;bHLH PAS protein JAP3;bHLH-PAS protein JAP3;bHLHe5;BMAL 1;BMAL1;BMAL1c;Brain and muscle ARNT like 1;Brain and muscle ARNT-like 1;CG8727 PA;Class E basic helix-loop-helix protein 5;cycle;JAP 3;JAP3;Member of PAS protein 3;Member of PAS superfamily 3;MGC47515;MOP 3;MOP3;PAS domain-containing protein 3;PASD 3;PASD3;TIC |
Swissprot | |
Calculated MW | 69kDa |
Cellular Localization | Nucleus. Cytoplasm. Nucleus, PML body. Shuttles between the nucleus and the cytoplasm and this nucleocytoplasmic shuttling is essential for the nuclear accumulation of CLOCK, target gene transcription and the degradation of the CLOCK-ARNTL/BMAL1 heterodimer. The sumoylated form localizes in the PML body. Sequestered to the cytoplasm in the presence of ID2. |
Concentration | 0.9 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol