ASCC1 Polyclonal Antibody

Uniprot : Q8N9N2
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14751

      Synonyms:Activating signal cointegrator 1 complex subunit 1,ASC-1 complex subunit p50,ASC1 complex subunit p50,ASC1p50,ASCC1,ASCC1,CGI 18,RP11-150D20.4,Trip4 complex subunit p50

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Activating signal cointegrator 1 complex subunit 1,ASC-1 complex subunit p50,ASC1 complex subunit p50,ASC1p50,ASCC1,ASCC1,CGI 18,RP11-150D20.4,Trip4 complex subunit p50
      Swissprot Q8N9N2
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human ASCC1
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm.
      Tissue specificity Ubiquitous.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ASCC1 Polyclonal Antibody at dilution 1:50

      Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ASCC1 Polyclonal Antibody at dilution 1:50

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