ASH2L Polyclonal Antibody

Uniprot : Q9UBL3
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14753

      Synonyms:ASH 2,Ash2 (absent small or homeotic) like,Ash2 (absent,small,or homeotic) like (Drosophila),ASH2,ASH2 LIKE,ASH2 like protein,ASH2-like protein,Ash2l,ASH2L,ASH2L1>,ASH2L2,Bre 2,Bre2,Discs 2-like,Drosophila absent,small,or homeotic,Drosophila ASH2-like,Set1/Ash2 histone methyltransferase complex subunit ASH2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms ASH 2,Ash2 (absent small or homeotic) like,Ash2 (absent,small,or homeotic) like (Drosophila),ASH2,ASH2 LIKE,ASH2 like protein,ASH2-like protein,Ash2l,ASH2L,ASH2L1>,ASH2L2,Bre 2,Bre2,Discs 2-like,Drosophila absent,small,or homeotic,Drosophila ASH2-like,Set1/Ash2 histone methyltransferase complex subunit ASH2
      Swissprot Q9UBL3
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human ASH2L
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus.
      Tissue specificity Ubiquitously expressed. Predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator. Alternative splicing results in a shorter isoform 2, designated ASH2L2, which is missing the first 94 amino acid residues found in ASH2L1. Human ASH2L proteins are 60% homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif. ASH2L is highly expressed in fetal liver, testis and leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami. 

      Images

      Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ASH2L Polyclonal Antibody at dilution 1:50

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ASH2L Polyclonal Antibody at dilution 1:50

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